Herpes, an
oral drug widely used to restrain the virus that causes genital herpes, seems
to decrease the rates of HIV in men who would not have genital herpes, based on a study by researchers in
the National Institutes of Health, Emory University, Case Western Reserve
University as well as the Civic Association of Health and Education in Lima,
Peru.
The research
is the first to demonstrate the drug will not need the existence of herpes
simplex virus 2 (HSV2) to curb HIV in patients. The research demonstrates that
HIV levels are likely reduced by the drug by interfering with the reproductive
machines of HIV.
The
researchers registered 18 HIV-infected individuals, none of whom was infected
with HSV2, and treated them. Two times a day, half of the subjects took
valacyclovir as well as the other half received a placebo. After fourteen days,
the placebo group received valacyclovir as well as another group received a
placebo. When valacyclovir was taken by the hsv singles , their blood HIV amounts decreased
significantly.
"This
study builds on our previously published work on the effect of acyclovir on
HIV-1.
A study by
the exact same research team in 2008 revealed that acyclovir suppresses HIV in
lab cultures of human tissues that have been infected with several types of
herpes viruses. Valacyclovir, which will be structurally much like acyclovir,
is converted to acyclovir within the body and remains in the blood more.
The primary
writers of the paper are Andrea Lisco and Christophe Vanpouille, both with
NICHD.
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